does zzzquil cause restless leg syndrome does zzzquil cause restless leg syndrome

I woke up roughly three hours after putting my head on the pillow with the absolute worst headache and stomachache Ive ever experienced in my entire life. Reviews that appear to be created by parties with a vested interest are not published. So, ZzzQuil. A: Typically, restless legs syndrome (RLS) affects one leg or both legs. Healthy fats include olive oil, avocado oil, and wild-caught seafood that are rich in omega-3 fatty acids. I gave it three days to work and each was the same. My room mate said I talked in my sleep the entire duration of my slumber, and my dreams were very vivid and unsettling. Also investigate other methods of reducing your blood pressure if possible. Histamine is a chemical that helps control alertness in the brain. In addition, she is a wife, mother, and the successful founder and CEO ofAmy Myers MD . This study represents an important step toward solving the longstanding mystery of restless legs syndrome and its disruptive impact on sleep, Brown said. By subscribing you agree to the Terms of Use and Privacy Policy. I think I am the problem but I'm sad that it wasn't effective the second time around as I woke up refreshed at 12:00am mind you I knocked out at 10:00pm-12:00am and now it's 3:30 am and I'm kinda tired but feel energized.". ZzzQuil Nighttime Sleep-Aid is an over-the-counter (OTC) medication that can help relieve occasional sleep problems. Here are some common restless legs triggers, plus tips to help you overcome them and get some sleep: Other health conditions can also cause restless legs. Restless legs syndrome affects between 20% and 30% of pregnant people. ", For Insomnia "I was using the liquid form and it was fine, working for me, but yesterday I took 2 of these pills, I slept for 5 hours, and now I have terrible headache. If you have questions about how much ZzzQuil you should take, talk with your doctor of pharmacist. Specifically, apprehensive behavior stresses the body. Still after tossing and turning for hours, I eventually made it to sleep, and felt as if I was awake the entire time. It is an autoimmune disease that occurs when the body begins attacking the joints, mistaking them as foreign invaders. Caffeine and alcohol are the two main foods that trigger restless legs syndrome symptoms or make them worse. (The symptoms were so severe that it was difficult to diagnose) I now take ropinerole (Requip) and it mostly has it under control. The purpose of the current study was to examine whether, in a controlled study, bupropion would improve the symptoms of RLS, or at least not exacerbate them. After adjusting for age, sex, race, BMI, blood donation frequency, and other factors, the researchers found that those who regularly consumed two or more different acid-blocking drugs were about twice as likely to have RLS compared with those who took none. When checking for iron deficiency, be sure to ask your doctor to test your ferritin levels, rather than the standard iron tests, which measure your hemoglobin and hematocrit levels. People with Restless Legs Syndrome are usually prompted to move because they feel intense sensations in their legs. It causes unpleasant sensations in the legs. ", For Insomnia "I have used ZzzQuil off and on for a year or so to help me fall asleep. 2 The sensations are difficult to describe: they are not painful but an uncomfortable "itchy", "Pins & Needles", or "creepy crawly" feeling deep in the legs. Your best bet would be to contact your doctor for some prescription sleep aids; maybe a sleep study if you got the insurance. The sensation is often worse in the evening or at night. So, what about using Zzzquil basically, Nyquil's cousin to help you sleep? My legs and feet were absolutely restless. Selected from data included with permission and copyrighted by First Databank, Inc. A person with restless legs syndrome experiences twitchiness and discomfort in the legs, usually after going to bed. One study found that women had significant relief of restless legs syndrome symptoms 4 weeks after giving birth.9 Estrogen levels drastically fall after giving birth. I felt like getting a REALLY good night's rest, so I grabbed a bottle of Vick's ZzzQuil, which as I'm sure you know, is a sleeping aid for when you're sick. I still feel really out of it, but my legs seem to be doing okay. All rights reserved. These can include: If you feel lightheaded while taking this medication, be sure to sit or lie down. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Genetics Home Reference. My multivitamin does not have iron in it, so its important to eat enough iron rich foods such as grass-fed beef, free-range, organic chicken, and wild-caught salmon. If we combine this information with your protected We avoid using tertiary references. Medications also help many people with RLS. Im totally throwing it away. Because restless legs syndrome is caused by underlying conditions, there is not a lab test or scan that can be used to diagnose restless legs syndrome. It typically happens in the evening or nighttime hours when you're sitting or lying down. Otherwise your going to continue to waste $ on useless OTC drugs when you could have saved that $ for the doctor or a sleep study", For Insomnia "I was trying to get my sleep schedule back on track since quarantine, so I turned to Zzzquil as opposed to my usual melatonin 10mg dose. I can't sit or work or concentrate. My Complete Omega-3 softgels are pharmaceutical grade, GMP certified, and 3rd party tested by Eurofins. I've struggled with insomnia since basically puberty, and few years back I began taking zzzquil daily. information submitted for this request. This chemical messenger plays a role in several key body functions such as learning, motivation, heart rate, blood flow, sleep, mood, learning, and movement. I didn't feel any effect from the medication until almost 10:30!! Good sources of protein include grass-fed beef, free-range chicken, and wild-caught fish. Restless legs syndrome causes are complex, however, you dont have to struggle with uncomfortable symptoms and sleepless nights. As a result, it may cause mild stomach upset. VICKS must remove this product , like NOW", For Insomnia "ZzzQuil seem to work well the first time I tried it. I couldn't keep them still for more than 10 seconds before I had to move them or get up and stretch or clench my leg muscles. 2003 Mar;4(2):121-32. doi: 10.1016/s1389-9457(02)00258-7. Lately my sleeping schedule is trash so I sleep around 5 am and wake up at 11 am and fully walk at 1:00pm and nap around 3-5 pm. 1996-2023 Everyday Health, Inc., a Ziff Davis company. I can say I was wildly disappointed with the results. Remember, the active ingredient in this medication is not a commonly abused medication. While past studies by other researchers found that blood iron deficiency may play a key role in the development of RLS, the current study did not find that, Earley said. So, when ZzzQuil blocks your histamine receptors, it causes drowsiness to help you sleep. Torture. ", For Insomnia "I personally wouldnt recommend this to my worst enemy. Talk with your health care provider if you think you may have RLS. Be sure to follow the dosage instructions on the package carefully. Restless legs syndrome (also called RLS) is a condition in which your legs feel very uncomfortable when you're sitting or lying down. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment. I heard orchestra music coming from the bathroom vent fan amidst its hum). The feelings usually occur while the affected person is sitting or lying down and are worse at night. Didnt work for me. It includes strong urges to move the legs, especially at night. Do not double your dose if you miss a dose. TSH levels of 1-2 UIU/ML or lower (Armour or compounded T3 can artificially suppress TSH). ", For Insomnia "If you have actual REAL insomnia ZzzQuil won't do a thing for you; I breathe great when I take it but no sleep. Bone Health Supplements: Are You Mineral Deficient? Looking for great essential oils, but dont know which brands are best? Conventional medicine tests for isolated hormones on their own, which will not pick up on whether your hormones are out of balance. Garcia-Borreguero D, et al. Some small studies have shown elevated rates of restless legs syndrome in people with other autoimmune diseases, such as lupus. What is the cause of restless legs syndrome? Healthy cognition, memory, learning, and focus can be improved with the addition of Neurocalm Mag in the evening as part of your bed time routine. Several studies have confirmed that cryotherapy can reduce inflammation. The appropriate use of opioids in the treatment of refractory restless legs syndrome. And it can be very frustrating. 1. The benefits of omega-3 fatty acids are widely publicized. "The discomfort that develops in the arms, back and legs is related to brain malfunction," Dr. Kotagal says. As MADlegs has advised, it's a calcium channel blocker and that may be the problem. I often wake up & can't go back to sleep for 90 minutes. if you're deciding on trying it , DO IT . ZzzQuil can affect your heart and blood vessels. I could fall asleep, but I would often wake hours earlier than I was supposed to and would wind up exhausted all day. 1 It may be especially helpful if the symptoms are perceived as less intense yet painful. The researchers explored the use of these PPI and H2A medications and the incidence of RLS among two different populations of blood donors in the United States and Denmark. More than 32 million people in the United States have been diagnosed with diabetes or prediabetes, a condition where your blood sugar is higher than normal levels, yet not high enough to be diagnosed with type 2 diabetes. It usually happens in the evening or night. Guidelines for the first-line treatment of restless legs syndrome/Willis-Ekbom disease, prevention and treatment of dopaminergic augmentation: A combined task force of the IRLSSG, EURLSSG, and the RLS-foundation. does zzzquil cause restless leg syndrome. Heart Disease in Women: Your Risks, Symptoms, and How to Prevent It, The Sleep Apnea Spectrum and What You Can Do About It, Natural Relief for Symptoms of Restless Legs Syndrome, Consider Supplements For Restless Legs Syndrome, Natural Relief for Restless Legs Syndrome Infographic Amy Myers MD, https://content.amymyersmd.com/article/causes-restless-legs-syndrome/. However, in my research, I've found that most antidepressants can cause the RLS symptoms to be worse or re-appear even on ropinerole. Honestly it has me feeling amazing just like other reviews. The movement is triggered by strange or uncomfortable feelings, often described as crawling, pulling, or itching, deep within both legs. In order to find relief, you first need to know what could be the root cause of your restless legs syndrome. RLS can lead to significant physical and emotional disability. Become aware of your restless legs triggers to relax. Call your doctor if any of these side effects bother you, get worse, or dont go away. It might work for others, just not me me. My melatonin and valerian root stopped working (even though I gave myself a week holiday). It can also cause an unpleasant crawling or creeping sensation in the feet, calves and thighs. Its been called the most common disease nobodys heard of and also one of the big mysteries in medicine. So many people are sleep-deprived, over-caffeinated, and burnt out. Here are 6 common causes of restless legs syndrome: Dopamine Imbalance Dopamine is a neurotransmitter released by the substantia nigra, which is located below the thalamus of the brain. She especially recommends taking a warm bath to help you wind down. I decided, fuck it, I'm going to drink a whole bunch of this stuff and soon enough I'll be fast asleep. Select a condition to view a list of medication options. No. Romulan is an Indica marijuana strain that has a high chance of reducing restless leg syndrome. NONE of this worked. It also shows the value of establishing collaborations with other research groups to enhance the quality and size of these studies., Although the disorder is complex and may also involve other biological mechanisms and other medications, RTIs Earley said he and his colleagues are optimistic about the findings. Whats more is that it doesnt get to the root cause of your restless legs syndrome. However, there are additional common symptoms that accompany restless legs syndrome. Read reviews and buy ZzzQuil Nighttime Sleep-Aid Liquid - Diphenhydramine HCl - Warming Berry Flavor at Target. Pregnancy or hormonal changes may temporarily worsen RLS signs and symptoms. restless legs syndrome, insomnia or narcolepsy," Watson said, noting that sleep aids like Nyquil or others are " not an appropriate therapy for these diseases," because they don't address "the root cause of the problem." Like walking, the toe circles stimulate the nerves in your legs; they also stretch the legs and feet. Silber MH. Thanks for reading. How do you choose the right allergy medication? I slowly grew a tolerant to it, and increased my dosage eventually to 100mg. Tried the ZZZquil last night and laid there for 3.5 hours before dozing off, then awake and tossing and turning every few minutes until morning. Restless. Your body also needs iron to make hormones such as cortisol, DHEA, and adrenaline. In fact, taking melatonin supplements may actually make RLS worse! This is whats called secondary restless legs syndrome: The Restless Legs Syndrome Foundation suggests using a sleep diary to pinpoint your personal triggers and gauge the severity of your symptoms. The defining symptom of restless legs syndrome is an overwhelming urge to move the legs, usually because of an uncomfortable sensation such as tingling, itching, throbbing, aching or feeling like electric shock. The donors completed blood count measures and an RLS diagnostic questionnaire. Ask your GP for an alternative med because these side effects will make your blood pressure higher through stress. Was surprised. Overview Restless legs syndrome (RLS) is a condition that causes an uncontrollable urge to move the legs, usually because of an uncomfortable sensation. Please contact your doctor or pharmacist. Hormonal changes during pregnancy, especially increases in the levels of estrogen and progesterone during the third trimester, are also likely a cause of restless legs syndrome. All rights reserved. We traced this symptom to the adverse effects of chronic stress. https://medlineplus.gov/genetics/condition/restless-legs-syndrome/. Restless legs syndrome (RLS), or Willis-Ekbom Disease, is a common and complex disorder characterized by an irresistible urge to move the legs, an urge often accompanied by unpleasant and abnormal sensations deep in the leg tissues such as itching, tingling, or crawling. Hi, I'm a 55 year old woman that has severe restless leg syndrome. ", For Insomnia "I used to work overnight so now I suffer from being in an opposite schedule. ", For Insomnia "I only took ZzzQuil for two nights. Allscripts EPSi. Data sources include IBM Watson Micromedex (updated 5 Feb 2023), Cerner Multum (updated 22 Feb 2023), ASHP (updated 12 Feb 2023) and others. This usually happens at bedtime but can occur during other times when your legs are inactive. Omega-3 fatty acids support a healthy inflammatory response and may help lower the risk of chronic diseases like heart disease, cancer, and arthritis. Labs such as Ulta Labs offer at-home tests for hemoglobin, liver and kidney function, and thyroid hormone levels. Share sensitive information only on official, secure websites. Normal levels for hemoglobins are 13.5 to 17.5 gm/dL for men and 12.0 or 15.5 gm/dL for women. Rheumatoid arthritis affects more than 1.3 million people in the United States. As I just mentioned, kidney disease inhibits the bodys ability to produce red blood cells to carry oxygen in the bloodstream. Sleep Medicine. You may opt-out of email communications at any time by clicking on https://www.ninds.nih.gov/Disorders/Patient-Caregiver-Education/Fact-Sheets/Restless-Legs-Syndrome-Fact-Sheet. Try setting an alarm to wake you up in the morning, as well as for bedtime. We think this work has the potential to have a significant and rapid clinical impact on the health of patients with RLS.. If you must have them, its best to use them in moderation. Occasionally, the arms are affected, too. I'm sure there isn't a product that exists that works for everyone. There's evidence to suggest restless legs syndrome is related to a problem with part . It can affect both men and women and occur at any age (including during childhood). A Pharmacist's Tips for a Good Night's Rest, The Do's and Don'ts of Cough and Cold Medicines. Magnesium is one of the most common nutritional deficiencies I saw in patients at my clinic. Cause Kicking Of The Feet All Night Long; Legs Can't Stop Moving; Restlessness Is Excessive In Legs; Creepy Crawlies . It never fails just as you crawl into bed, your restless legs start acting up again. RESTLESS legs syndrome (RLS) is characterized by sensory (urge to move, usually associated with legs paresthesia and dysesthesia) and motor (voluntary and involuntary leg movements) symptoms occurring selectively when the individual is at rest, during the evening and night. Accessed Nov. 16, 2021. Whats more is that dopamine levels naturally decline towards the end of the day, which could explain why symptoms worsen in the evening. Myers specializes in empowering those with autoimmune, thyroid, and digestive issues to reverse their conditions and take back their health. The team examined 117 people with MS and 118 people without the disease. a type of movement disorder called parkinsonism, extrapyramidal symptoms as a result of taking the medication, inflammation of the nose due to an allergy, a significant type of allergic reaction called anaphylaxis, an increase in the thickness of lung secretions, a type of blood disorder where the red blood cells burst called hemolytic anemia, an extreme sense of wellbeing called euphoria, increased sensitivity of the skin to the sun, a feeling of general discomfort called malaise, a type of bumpy skin rash called a maculopapular rash. Gabapentin can be used to treat the symptoms of restless legs syndrome (RLS). I custom-formulated The Myers Way Multivitamin to provide the widest range possible of the most critical vitamins and minerals in their most usable forms, which means methylated B vitamins, including 500 mcg of vitamin B12 and 400 mcg of folate to promote a healthy inflammatory response. We live on a farm and have 3 outside dogs that like to bark at night. Ive tried melatonin and sleepy tea with no success, but I was desperate and gave zzzquil a try. In fact, in most cases, there's no known cause for restless leg syndrome. However, it sometimes accompanies other conditions, such as: Although RLS doesn't lead to other serious conditions, symptoms can range from barely bothersome to incapacitating. Does ZzzQuil interact with other medications? But if I take a 1/2 dose of ZZZquil, I can fall right back to sleep. 8816 Cullen Ln, Austin, TX 78748, 2016-2023 AMMD, LLC (AmyMyersMD.com). An official website of the United States government. Valerian is an herb used to promote relaxation and sleep. Do Toe Circles. Its also difficult to treat, as there are few effective medications or therapies for relieving the symptoms of the disorder, which has no known cure. Your doctor can test your iron levels with a standard blood test. I found that the following ranges for hormone levels are where my patients at my clinic (and myself) thrived, not just lived: Remember, it is the individual level of each hormone that determines if your hormones are in balance. The researchers chose to study antacids because a growing number of studies have shown a link between these drugs and iron deficiency. A single copy of these materials may be reprinted for noncommercial personal use only. Please, if you have not tried DPH before, don't do it. I felt like my body was made of lead, and was horribly lethargic. Diabetes is a major health issue across the world. Call your doctor if mild side effects bother you, get worse, or dont go away. What a waste of money. Neurocalm Mag is the very best form of magnesium for brain health, cognitive function, relaxed sleep and a healthy mood. Accessed Nov. 16, 2021. This product is a joke and a nightmare for people that can't sleep. ", For Insomnia "I have insomnia for the past several months and a friend told me to try ZzzQuil. Caffeine and alcohol are toxic foods, and should be avoided. However, like most drugs, ZzzQuil may cause some side effects. Talk to your doctor if you think this medication isnt helping you sleep. Treating these conditions will often calm the restless legs. A lock ( A locked padlock) or https:// means youve safely connected to the .gov website. Pramipexole is a dopamine agonist (mimics the effects of the neurotransmitter dopamine) that may be used in the treatment of Parkinson's disease and Restless Legs Syndrome. Restless legs syndrome (RLS) is a sleep disorder in which uncomfortable leg sensations create an uncontrollable urge to move your legs. As a result, less hemoglobin an iron rich protein that acts as an oxygen taxi production occurs, which further increases fatigue and muscle movement, also associated with RLS. Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. For instant relief from restless legs at night, Dr. Matta suggests finding a bedtime routine that primes your body to relax before RLS can kick in. I took it at 10:00 p.m. and went to bed 30 minutes later, but still can't sleep the entire night. A few of its most notable roles are supporting healthy bowels, maintaining healthy bones, aiding in cognitive function, relaxing tight and aching muscles, and, perhaps most importantly, supporting cardiovascular health. 2016; doi:10.1212/WNL.0000000000003388. Your substantia nigra synthesises the amino acid tyrosine into a substance called dopa, which then turns into dopamine. All it did was make me feel very relaxed. Patients with RLS may report sensations, such as an almost irresistible urge to move the legs, that are not painful but are distinctly bothersome. Here are the 8 best magnesium supplements, Healthline has strict sourcing guidelines and relies on peer-reviewed studies, academic research institutions, and medical associations. Sensations that get worse after laying down or spending a long period of time sitting in a car, airplane, or a movie theater. A body that becomes chronically stressed can exhibit symptoms of stress. Conventional medicine treats RLS with harsh medications such as Requip, Mirapex, Horizant, and Neupro.1 These medications have harsh side effects such as stomach pain, constipation, nausea, vomiting or diarrhea. This article explains all you need to know about valerian and its effects and safety. Use these dosage charts for infants and children under 12 years old: amitriptyline, lorazepam, melatonin, zolpidem, diphenhydramine, Ativan. ZzzQuil can cause side effects to the nervous system, which includes your brain and spinal cord. ZzzQuil can negatively affect your urinary system if you take too much. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. Feel free to comment about your experiences so I can better understand what the hell happened last night. Live Chat with us, Monday through Friday, 8:30 a.m. to 5:00 p.m. EST. Here are 6 common causes of restless legs syndrome: Dopamine is a neurotransmitter released by the substantia nigra, which is located below the thalamus of the brain. Get Your Nutrients on the Go with Travel-Friendly Single-Serves. You get temporary relief with movement such as stretching, jiggling your legs, or walking. The study focused on two types of potent medications that directly inhibit stomach acid secretionproton pump inhibitors (PPI) and histamine type 2 receptor antagonists (H2A). Symptoms, Causes, Diagnosis, Treatment, and Prevention, What Is Sleep Apnea? privacy practices. For all those people saying it doesn't work, it just doesn't work for them. Restless legs syndrome (RLS) is a condition that causes an uncontrollable urge to move the legs, usually because of an uncomfortable sensation. The study, published in the journal SLEEP, was funded in part by the National Heart, Lung, and Blood Institute (NHLBI). I took two. The sensations are described as: Creeping Crawling Tingling Pulling You usually have these sensations in the calf, but they may be felt anywhere from the thigh to the ankle. I took the recommended dose (2pills) at 8pm. 1998-2023 Mayo Foundation for Medical Education and Research (MFMER). ZzzQuil Nighttime Sleep-Aid may cause other possible side effects, so be sure to read the package before using the product. They may also consider it a movement disorder, as people must move their legs to ease symptoms. When no cause can be found, it's known as idiopathic or primary restless legs syndrome. The cause of RLS is unknown in most cases but could include hormonal changes, iron deficiency, certain medications, or illnesses. It often worsens with age and becomes a problem for older adults. People Are Taking High Doses of Melatonin to Sleep: Why Experts Are Concerned, How Valerian Root Helps You Relax and Sleep Better, The 8 Best Magnesium Supplements for Sleep, hallucinations (seeing or hearing things that arent real), dangerously low blood pressure, which can cause lightheadedness, eye and vision problems, such as blurry vision and extremely dry eyes. Walters AS, LeBrocq C, Dhar A, Hening W, Rosen R, Allen RP, Trenkwalder C; International Restless Legs Syndrome Study Group. In general, taking this medication only from time to time should keep side effects to a minimum. (2013, June), ZzzQuil Nighttime Sleep-Aid diphenhydramine hydrochloride liquid. Its true that alcohol is a depressant that slows down your nervous system. Restless Leg Syndrome (RLS, Myoclonus, Akathisia) is a disorder in which there is an urge or need to move the legs to stop unpleasant sensations. Many people with RLS find it difficult to fall or stay asleep. Xu XM, et al. . It's restless legs syndrome (RLS), a neurological and sleep disorder that causes discomfort and sometimes pain in the legs, particularly at night. People with RLS usually don't describe the condition as a muscle cramp or numbness. Amy Myers, MD is a two-time New York Times bestselling author an an internationally acclaimed functional medicine physician.Dr. Breaking Out in Hives When You're Nervous? Receive automatic alerts about NHLBI related news and highlights from across the Institute. A primary cause of this is, not surprisingly, iron deficiency. A primary cause of this is, not surprisingly, iron deficiency. Silber MH, et al. Studies have shown that restless legs syndrome is more common in patients with type 2 diabetes than those with type 1 diabetes. This adversely affects the overall performance and mental peace of the person. Research has identified specific genes related to restless legs syndrome, and it can run in families. These side effects are largely caused by the drugs blocking of the receptors for histamine and acetylcholine, and they can impact different parts of your body. If your symptoms develop before the age of 45, it is more likely that you have a first-degree relative such as a parent or sibling with RLS. Terrible pill, will not take it again. Lately, Ive had trouble falling asleep in addition to staying asleep. National Institute of Neurological Disorders and Stroke. And then I woke up again at 12:30am! In order to find relief, you have to get to the root cause of your symptoms. Lets dive more into the symptoms of restless legs syndrome. Things to remember when you fill your prescription. Mayo Clinic. View detailed reports from patients taking Diphenhydramine Hydrochloride who experienced restless legs syndrome. An hour later I was watching the walls ripple like the surface of a pond, little black dots crawling up the walls here and there, and full blown auditory hallucinations. One of the best home remedies for restless leg syndrome symptoms is applying the apple cider vinegar. Lets talk about restless legs syndrome causes. Available for Android and iOS devices. Some studies have found a higher incidence of RLS among people with iron deficiency. It typically happens in the evening or nighttime hours when you're sitting or lying down. 2018; doi:10.1016/j.smrv.2017.06.003. Cytokines, particularly the interleukins (abbreviated as IL), control cell signaling in an immune system response and support a healthy inflammatory response. Symptoms are often most severe at night when a person is sitting or lying in bed. 2. Medications may be most effective for severe RLS, but identifying and avoiding things that aggravate your symptoms can also help, especially in mild or moderate cases. ZZZQuil actually had the opposite effect than what it promised. Side Effects of Melatonin: What Are the Risks? Sorry, we have no data available. Restless legs syndrome causes sleep disturbances, is associated with anxiety and depression, and has a negative effect on quality of life. Sleep Medicine Reviews. Some women get RLS for the first time during pregnancy, especially during their last trimester. was really disappointed Actually it woke me up even more or I laid super restless for hours after taking", For Insomnia "Trying to get off enormous amount of THC full CBD which helps sleeps a bit but makes me wonky.